AcroPak™ 500, 1000, & 1500 Capsules with Supor® Membrane

Fast, final filtration and high throughputs with Supor membrane for liquid volumes up to 150 liters

Ensure sterile, mycoplasma-free cell culture media with AcroPak capsules with 0.1 µm Supor membrane.
Provide higher throughputs and faster flow rates than similar-size competitive devices.
Save money by increasing throughput with available built-in prefilter in the AcroPak capsule with Supor membrane.
100% integrity tested to assure sterile filtrate.
Fusion-welded components eliminate the potential for release of extractables from sealing adhesives.
Easy scale up to larger Supor membrane capsules and cartridges from Pall.
Ideal for solutions requiring low protein binding.
Sterilized by gamma irradiation to eliminate potential contamination by EtO residuals.

Use for filtration of batches up to 50 liters (AcroPak™ 500 capsules, formerly SuporCap™ 50, CritiCap™, and CritiCap-M capsules), 100 liters (AcroPak 1000 capsules, formerly SuporCap 100, CritiCap, and CritiCap-M capsules) and 150 liters (AcroPak 1500 capsule) for applications such as:

Large volume media preparation.
Pilot scale manufacturing.
Liquids requiring prefiltration, such as serum-containing media.
Sterile filtration of buffers.
Point-of-use filtration for laboratory water.
Reduce mycoplasma with the 0.1 µm pore size.

Materials of Construction
Filter Media: Supor membrane (hydrophilic polyethersulfone)
Housing, Vent Plug, and Filter Support: Polypropylene
Sealing Method: Thermal bonding
Filling Bell: Polycarbonate

Pore Size
0.1/0.1, 0.2/0.2, 0.8/0.2 and 0.8/0.45 µm

Effective Filtration Area
AcroPak 500 capsules: 500 cm²
AcroPak 1000 capsules: 1000 cm²AcroPak 1500 capsules: 1500 cm²Dimensions
Diameter: 6.9 cm (2.7 in.)
Overall Length (without Filling Bell):
500 series: 14.5 cm (5.7 in.)
1000 series: 19.3 cm (7.6 in.)
1500 series: 22.9 cm (9.0 in.)

Inlet/Outlet Connections
AcroPak 500 & 1000 series:
6.4 - 12.7 mm (1/4 - 1/2 in.) stepped hose barb with filling bell on outlet

AcroPak 1500 series:
12.7 mm (1/2 in.) straight hose barb, no filling bell on outlet

Typical Hold-up Volume
(with 10 psi air purge)
500 series: 30 mL
1000 series: 45 mL
1500 series: N/A

Maximum Operating Temperature
60 °C (140 °F) at 2.1 bar (210 kPa, 30 psi)

Maximum Operating Pressure
Continuous: 4.1 bar (410 kPa, 60 psi) at ambient temperature

Recommended Integrity Test
Minimum Bubble Point — Water
0.2 µm: 3.5 bar (350 kPa, 51 psi)
0.45 µm: 1.7 bar (170 kPa, 24 psi)
60% IPA/40% H₂O (v:v)
0.1 µm: 2.4 bar (240 kPa, 35 psi)

Typical Water Flow Rate
L/min at 0.07 bar (7 kPa, 1 psi)


	500 series	1000 series	1500 series

0.1/0.1 µm	0.2 (0.2)	0.4 (0.3)

0.2/0.2 µm	0.6 (0.4)	1.1 (0.8)	1.6 (1.1)

0.8/0.2 µm	1.1 (0.8)	1.6 (1.1)	2.2 (1.5)

0.8/0.45 µm	1.3 (0.9)	2.5 (1.7)

Bacterial Retention
0.1/0.1 µm capsules: Lot samples retain a minimum of 10⁷ cfu/cm² of A. laidlawii challenge per modified ASTM F838-83
0.2 µm capsules: Lot samples retain a minimum of 10⁷ cfu/cm² of B. diminuta per modified ASTM F838-83

Endotoxin Level
< 0.25 EU/mL using Limulus Amoebocyte Lysate (LAL) test

Biological Safety
Passes United States Pharmacopeia (USP) Biological Reactivity Test, In Vivo <88>

Sterilization
Sterilized by gamma irradiation; if desired, autoclave once only prior to use at 121 - 123 °C (250 - 253 °F) for a maximum of 20 minutes.

Total Throughput Recorded for Devices with
an EFA of Up to 1000 cm²

Built-in Prefilter Enhances Total Throughput

AcroPak 500 Capsules with Supor Membrane
Part Number	Description	Pkg	Price	Qty
12997	0.1/0.1 µm, sterile	1/pkg	99.78
12995	0.2/0.2 µm, sterile	1/pkg	95.57
12991	0.8/0.2 µm, sterile	1/pkg	82.85
12993	0.8/0.45 µm, sterile	1/pkg	81.55
AcroPak 1000 Capsules with Supor Membrane
12999	0.1/0.1 µm, sterile	1/pkg	143.00
12996	0.2/0.2 µm, sterile	1/pkg	129.83
12992	0.8/0.2 µm, sterile	1/pkg	126.19
12994	0.8/0.45 µm, sterile	1/pkg	123.18
AcroPak 1500 Capsules with Supor Membrane
12686	0.2/0.2 µm, sterile	1/pkg	156.01
12675	0.8/0.2 µm, sterile	1/pkg	149.20

Contact Customer Service at 800-521-1520 for possible lead-time and date item will be available to ship.