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Acrodisc® Syringe Filters with GHP Membrane and GHP Membrane Discs for Analytical Samples

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Acrodisc® Syringe Filters with GHP Membrane and GHP Membrane Discs for Analytical Samples
The "universal" membrane filter for all of your analytical filtration requirements
  • AutoPack™ packaging is easy to use and the Caliper** Automation Preferred™ certification assures you of smooth operation and worry-free performance 24 hours a day in automated workstations.
  • Avoid the expense and inconvenience of keeping a variety of filters on hand. Versatile filter for aqueous and aggressive organic solvent-based solutions.
  • Low protein binding membrane gives high recovery of critical proteinaceous samples.
  • Accurate analysis. HPLC certified for low levels of UV-absorbing extractables.
  • Easy filtration of particulate-laden samples with glass fiber prefilter version.
  • 13 mm Acrodisc syringe filter with minispike configuration offers low hold up and easy filtration into autosampler vials.

**Caliper Life Sciences was previously Zymark Corporation

  • Highly recommended for filtering HPLC samples and mobile phases.
  • The Acrodisc PSF GxF syringe filter provides two to four times the throughput of standard prefilter devices for extremely viscous samples.
  • Acrodisc PSF syringe filter is available in robotic-compatible AutoPack™ packaging for Caliper Prelude* , TPWII, and Multi-Dose* systems and Sotax* dissolution systems.
Acrodisc Syringe Filters with GHP Membrane
Materials of Construction
Filter Media: GH Polypro (GHP) membrane (hydrophilic polypropylene)
Housing: Polypropylene
GxF Prefilter: Binder-free borosilicate glass

Pore Size

0.2 and 0.45 µm

Effective Filtration Area

13 mm: 1.0 cm2
25 mm PSF: 3.9 cm2

Sample Volume
13 mm: < 10 mL
25 mm PSF: < 150 mL

Inlet/Outlet Connections
13 mm: Female Luer-Lok* inlet, minispike outlet
25 mm PSF: Female Luer-Lok* inlet, male slip luer outlet

Typical Hold-up Volume
(with air purge)
13 mm: < 14 µL
25 mm PSF: < 125 µL
25 mm PSF GxF: < 200 µL

Maximum Operating Temperature
55 °C (131 °F)

Maximum Operating Pressure
13 mm: 6.3 bar (630 kPa, 90 psi)
25 mm PSF: 4.1 bar (410 kPa, 60 psi) at
   21 - 24 ºC (70 - 75 ºF); 2.1 bar (210 kPa, 30 psi) at 55 ºC (131 ºF)

Typical Water Flow Rate
mL/min at 0.7 bar (70 kPa, 10 psi)
13 mm, 0.2 µm: 17
13 mm, 0.45 µm: 28

mL/min at 2.1 bar (210 kPa, 30 psi)
25 mm PSF, 0.2 µm and
   GxF/0.2 µm: 175
25 mm PSF, 0.45 µm and
   GxF/0.45 µm: 195

GH Polypro (GHP) Membrane Disc Filters
Filter Media
Hydrophilic polypropylene

Pore Size
0.2 and 0.45 µm

Typical Thickness
0.2 µm: 101 µm (4.0 mils)
0.45 µm: 114 µm (4.5 mils)

Typical Water Flow Rate
mL/min/cmat 0.7 bar (70 kPa, 10 psi)
0.2 µm: 20
0.45 µm: 31

Maximum Operating Temperature
55 °C (131 °F)

Minimum Bubble Point — Water
0.2 µm: 2.9 bar (290 kPa, 42 psi)
0.45 µm: 1.38 bar (138 kPa, 20 psi)

GH Polypro (GHP) Membrane is Extremely Low in Biomolecule Binding

125I-labeled BSA (1.6 µg) or 32P-labeled DNA (500 ng) were diluted to 5 mL in PBS (BSA) or Tris-EDTA (DNA) and filtered through a 13 mm disc of the indicated membrane. Filtration was carried out using a 10 mL syringe at a flow rate of 1.0 mL/min. Binding was determined by comparing the amount of radioactivity remaining in the membrane (triplicate) to the activity of the starting material by placing the disc or solution directly into scintillation cocktail and counting in a scintillation counter. Biodyne B membrane is designed for biomolecule binding and was used as a positive control.

Part Number Description Pkg Price Qty
Acrodisc Syringe Filters with GHP Membrane, 13 mm
4554 0.2 µm, minispike outlet 100/pkg 300/cs 628.99
4567 0.2 µm, minispike outlet 1000/pkg 1,170.31
4556 0.45 µm, minispike outlet 100/pkg 300/cs 628.99
4563 0.45 µm, minispike outlet 1000/pkg 1,170.31
Acrodisc PSF Syringe Filters with GHP Membrane, 25 mm
AP-4364 0.2 µm, AutoPack™ tubes 25/pkg 200/cs 509.65
AP-4564 0.2 µm 50/pkg 200/cs 532.82
AP-4566 0.2 µm 1000/pkg 1,700.09
AP-4357 0.45 µm, AutoPack tubes 25/pkg 200/cs 509.65
AP-4560 0.45 µm 50/pkg 200/cs 532.82
AP-4562 0.45 µm 1000/pkg 1,700.09
Acrodisc PSF GxF Syringe Filters with GHP Membrane, 25 mm
AP-4305 GxF/0.2 µm, AutoPack tubes 25/pkg 200/cs 577.62
AP-4307 GxF/0.2 µm 50/pkg 200/cs 577.62
AP-4306 GxF/0.2 µm 1000/pkg 2,068.29
AP-4557 GxF/0.45 µm, AutoPack tubes 25/pkg 200/cs 577.62
AP-4559 GxF/0.45 µm 50/pkg 200/cs 577.62
AP-4558 GxF/0.45 µm 1000/pkg 2,068.29
GHP Membrane Disc Filters, 0.2 µm
66557 47 mm 100/pkg 143.42
66628 50 mm 100/pkg 157.88
GHP Membrane Disc Filters, 0.45 µm
66629 13 mm 100/pkg 101.14
66340 25 mm 100/pkg 101.14
66640 37 mm 100/pkg 134.21
66548 47 mm 100/pkg 143.42
66625 50 mm 100/pkg 157.88
66626 90 mm 100/pkg 328.90


Contact Customer Service at 800-521-1520 for possible lead-time and date item will be available to ship.



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*US List Price applies only to products delivered within the US. These prices do not reflect duties, taxes or tariffs, which may apply to purchases made outside of the US. See our General Limited Warranty.